abstract：:Dendropanax trifidus Makino (family Araliaceae, syn. Gilibertia trifida Makino) has been reported as causing allergic contact dermatitis in Japan. To identify the major allergen, fractionated extracts of fresh leaves of Dendropanax trifidus were patch tested on 2 patients with hypersensitivity to the plant. Cis-9,17-o...

journal_title：Contact dermatitis

authors： Oka K,Saito F,Yasuhara T,Sugimoto A

更新日期：1997-05-01 00:00:00

abstract：:The irritant potential of calcipotriol, 1 alpha,24-dihydroxyvitamin D3 (tacalcitol) and 1 alpha,25-dihydroxy-vitamin D3 (calcitriol) was compared in a hairless guinea pig model, Randomized, occlusive patch testing for 2 days was used. Each group of 8 animals was tested simultaneously with the 3 substances and a placeb...

journal_title：Contact dermatitis

authors： Fullerton A,Serup J

更新日期：1997-04-01 00:00:00

abstract：:Whilst patch testing with corticosteroids in ethanol is more sensitive than either petrolatum or the cream formulation, the frequency of false-negative reactions is not known. We have compared patch testing with corticosteroid at 1% in ethanol with intradermal (i.d.) tests using 1 mg corticosteroid suspended in normal...

journal_title：Contact dermatitis

authors： Seukeran DC,Wilkinson SM,Beck MH

更新日期：1997-03-01 00:00:00

abstract：:Adverse cutaneous reactions to topically applied olive oil are seldom reported, and positive patch tests to it are mostly regarded as allergic. To evaluate such "positive" patch test reactions, 77 female (mean age: 44 years) and 23 male eczema patients (mean age: 46 years) were prospectively patch tested with freshly ...

journal_title：Contact dermatitis

authors： Kränke B,Komericki P,Aberer W

更新日期：1997-01-01 00:00:00

abstract：:The epidermal response to 2 different irritants, nonanoic acid (NAA) and sodium lauryl sulfate (SLS), was investigated with 2 different methods. NAA 80% and SLS 4% were applied under occlusion for up to 24 h. Elemental changes were determined in cryosections by x-ray microanalysis. Compared to unexposed skin a signifi...

journal_title：Contact dermatitis

authors： Grängsjö A,Leijon-Kuligowski A,Törmä H,Roomans GM,Lindberg M

更新日期：1996-12-01 00:00:00

abstract：:The Nickel Directive will become law in the countries of the European Union in 1996. This directive states that the concentration of nickel in post assemblies (used after ear piercing) may not exceed 0.05%, that products which come into direct and prolonged contact with the skin, e.g. earrings, watchstraps or zippers,...

journal_title：Contact dermatitis

authors： Gawkrodger DJ

更新日期：1996-11-01 00:00:00

abstract：:We studied 39 patients with erythema-dyschromicum-perstans-like dermatitis seen at Changuinola Hospital in Panama. They were compared with 41 controls. The 2 groups were native field workers of the banana plantations exposed to many pesticides. In 34 patients, there was a positive patch test reaction to 2,4,5,6-1,3-te...

journal_title：Contact dermatitis

authors： Penagos H,Jimenez V,Fallas V,O'Malley M,Maibach HI

更新日期：1996-10-01 00:00:00

abstract：:Patch testing, using European standard allergens and suspected causative substances brought in by patients, was carried out in 490 patients with eczema in Hong Kong and 437 completed the test. Before patch testing, 244, 141 and 105 patients were diagnosed as having contact dermatitis, endogenous eczema and unclassifie...

journal_title：Contact dermatitis

authors： Lee TY,Lam TH

更新日期：1996-07-01 00:00:00

abstract：:Sensitization rates are influenced by sex and age. Crude rates from different departments cannot be compared without taking into account these variables. However, the influence of sex and age has never been considered quantitatively. In 2 hypothetical populations with identical age-specific sensitizations rates, but d...

journal_title：Contact dermatitis

authors： Schnuch A

更新日期：1996-06-01 00:00:00

abstract：:In the present study, we have investigated 42 cosmetic products based on natural ingredients for content of 11 fragrance substances: geraniol, hydroxycitronellal, eugenol, isoeugenol, cinnamic aldehyde, cinnamic alcohol, alpha-amylcinnamic aldehyde, citral, coumarin, dihydrocoumarin and alpha-hexylcinnamic aldehyde. T...

journal_title：Contact dermatitis

authors： Rastogi SC,Johansen JD,Menné T

更新日期：1996-06-01 00:00:00

abstract：:The correct concentration and vehicle for patch testing with corticosteroids is in many instances not known. The results of this study suggest that 1% in ethanol should be the initial choice, unless it can be shown that petrolatum as a vehicle is as sensitive (tixocortol pivalate and budesonide). We could find no evid...

journal_title：Contact dermatitis

authors： Wilkinson SM,Beck MH

更新日期：1996-05-01 00:00:00

abstract：:Numerous studies have focused attention on the influence of various biological and environmental factors on contact hypersensitivity. In order to evaluate the persistence and/or modification of allergic contact sensitivity to a number of common contact sensitizers, the same standardized patch tests were repeated on 17...

journal_title：Contact dermatitis

authors： Ayala F,Balato N,Lembo G,Patruno C,Fabbrocini G,Nofroni I,Magliocchetti N,Schena D,Rafanelli A,Seidenari S,Motolese A,Angelini G,Tosti A,Saccabusi S,Pigatto P,Lisi P

更新日期：1996-05-01 00:00:00

abstract：:The development of hand eczema was evaluated in an 8-year follow-up study carried out in 51 junior hairdressers. Predisposing factors were investigated. Data were collected by use of a self-administered questionnaire: 74% response. None of the junior hairdressers presented with hand eczema at the start of the survey. ...

journal_title：Contact dermatitis

authors： Majoie IM,von Blomberg BM,Bruynzeel DP

更新日期：1996-04-01 00:00:00

abstract：:As part of the investigation of sources of exposure to rosin allergens, disposable diapers (napkins) common on the Swedish market were analyzed, using gas chromatography, to detect the main rosin compounds. Rosin components were detected in all diapers, the highest amounts in those from the 2 major producers. In these...

journal_title：Contact dermatitis

authors： Karlberg AT,Magnusson K

更新日期：1996-03-01 00:00:00

abstract：:This study presents a profile of patients with chronic recalcitrant eczematous disease referred by dermatologists for contact allergy evaluation. Allergic contact dermatitis (ACD) and irritant responses were carefully defined, as was the presence or absence of atopy obtained by history. Of 410 patients studied, 44% ha...

journal_title：Contact dermatitis

authors： Klas PA,Corey G,Storrs FJ,Chan SC,Hanifin JM

更新日期：1996-02-01 00:00:00

abstract：:Rubber chemicals are among the most common occupational contact sensitizers. The most common rubber sensitizers are thiurams, thiazoles, carbamates and paraphenylenediamine derivatives. Here we present data on a less-well-known rubber chemical, N-(cyclohexylthio)phthalimide (CTP; CAS 17796-82-6). This chemical is curr...

journal_title：Contact dermatitis

authors： Kanerva L,Estlander T,Jolanki R

更新日期：1996-01-01 00:00:00

abstract：:Occupational skin disease is one of the most common occupational diseases. The hand is the most frequent site of involvement in occupational skin disease. We interviewed and examined patients seen in the Contact Dermatitis Clinic of the National Taiwan University Medical Center, a tertiary referral center in Taipei Ci...

journal_title：Contact dermatitis

authors： Sun CC,Guo YL,Lin RS

更新日期：1995-12-01 00:00:00

abstract：:Plants from the Verbenaceae family may cause contact dermatitis of unknown nature. This report describes 2 cases of allergic reactions to the Verbena species. A teenage boy developed an anaphylactic allergic response following contact with the leaves of Verbena hybrida. Characterization of the patient's specific IgE r...

journal_title：Contact dermatitis

authors： Potter PC,Mather S,Lockey P,Knottenbelt JD,Paulsen E,Skov PS,Andersen KE

更新日期：1995-11-01 00:00:00

abstract：:Surface-active agents (surfactants) are characterized by the possession of 2 different moieties, both polar and non-polar regions on the same molecule. Surfactants are broadly classified as anionic, cationic, amphoteric, or non-ionic, according to the nature of the hydrophile yielded in aqueous solution. In currently ...

journal_title：Contact dermatitis

authors： Effendy I,Maibach HI

更新日期：1995-10-01 00:00:00

abstract：:Data suggests that protection from gloves is paradoxically reduced because of effects of occlusion on the skin. The aim of this study was to characterize these effects on physical and functional properties of stratum corneum. Volunteer trials were conducted using patches of polyvinyl chloride (PVC) glove material on t...

journal_title：Contact dermatitis

authors： Graves CJ,Edwards C,Marks R

更新日期：1995-09-01 00:00:00

abstract：:Miconidin (2-methoxy-6-pentyl-1,4-dihydroxybenzene) and the allergen primin (2-methoxy-6-pentyl-1,4-benzoquinone) have been isolated from fresh unchopped plant material (leaves, stems and flowers together) of Primula obconica. Miconidin and primin were obtained in approximately equal amounts and their structures deter...

journal_title：Contact dermatitis

authors： Krebs M,Christensen LP

更新日期：1995-08-01 00:00:00

abstract：:Skin compatibility of anionic surfactants may often but not always be predicted by in vitro tests. For instance, the correlation between in vivo and in vitro data is classically hampered in the presence of magnesium. This ion is known to interfere with in vitro skin irritation predictive tests based on protein denatur...

journal_title：Contact dermatitis

authors： Goffin V,Paye M,Piérard GE

更新日期：1995-07-01 00:00:00

abstract：:The dose- and time-related effect of sodium lauryl sulfate (SLS) on in vitro percutaneous penetration was studied using 3 radiolabeled tracer compounds with different physicochemical properties: tritiated water, hydrocortisone and nickel. Human cadaver abdominal skin from caucasian women was used as membrane in static...

journal_title：Contact dermatitis

authors： Frankild S,Andersen KE,Nielsen GD

更新日期：1995-06-01 00:00:00

abstract：:The frequencies of cosmetics intolerance and contact allergy to colophony were investigated among 116 singers and dancers and 16 make-up artists. Participants were interviewed, examined and patch tested with a standard series and materials from the opera house. Common skin lesions were found in 1/3 of participants and...

journal_title：Contact dermatitis

authors： Färm G,Karlberg AT,Lidén C

更新日期：1995-05-01 00:00:00

abstract：:Contact allergy to corticosteroids now seems frequent among patients being patch tested. As corticosteroids are intrinsically anti-inflammatory, we investigated whether patch tests with a potent corticosteroid might suppress simultaneous adjacent patch test reactions to another allergen. Nickel-sensitive subjects were...

journal_title：Contact dermatitis

authors： Bruze M,Isaksson M,Dooms-Goossens A

更新日期：1995-03-01 00:00:00

abstract：:A dermatologic investigation of 202 construction painters included patch testing with the TRUE Test standard series and ingredients of water-based paints, glues and putties (painters' series). 32 painters had current eczema and 16 had a history of previous eczema. Of these, 16 and 9, respectively, had current and prev...

journal_title：Contact dermatitis

authors： Fischer T,Bohlin S,Edling C,Rystedt I,Wieslander G

更新日期：1995-01-01 00:00:00

abstract：:Kojic acid (5-hydroxy-2-(hydroxymethyl)-4-pyrone), a fungal metabolic product, has increasingly been used as a skin-depigmenting agent in skin care products marketed in Japan since 1988. In order to determine its frequency of sensitization, during 1 year from October 1992 to September 1993, we performed patch testing ...

journal_title：Contact dermatitis

authors： Nakagawa M,Kawai K,Kawai K

更新日期：1995-01-01 00:00:00

abstract：:Thiourea compounds are mainly used as accelerators in the rubber industry, but also in other industries, e.g., as antioxidants in the graphics industry. Thiourea compounds may provoke allergic contact dermatitis, although the number of reported cases is relatively low. During 1985-1991, we had 5 patients with allergic...

journal_title：Contact dermatitis

authors： Kanerva L,Estlander T,Jolanki R

更新日期：1994-10-01 00:00:00

abstract：:We report a case of hypertrophic allergic contact dermatitis probably due to p-phenylenediamine (PPDA) in a 26-year-old female, which developed at the sites of application of a black hair dye to the skin. Histological examination revealed an eczematous process. The lesions subsided completely except for leukoderma tha...

journal_title：Contact dermatitis

authors： Santucci B,Cristaudo A,Cannistraci C,Amantea A,Picardo M

更新日期：1994-09-01 00:00:00

abstract：:We compared the incidence of occupational dermatitis and transepidermal water vapour loss (TEWL) changes from cutting fluids (neat mineral oils) in 24 new machinists with 27 armed forces paramedics (controls) over a 6-month period. The cumulative incidence of occupational dermatitis in positive controls increased from...

journal_title：Contact dermatitis

authors： Goh CL,Gan SL

更新日期：1994-08-01 00:00:00

abstract：:We have examined 6 construction workers who developed chronic skin diseases on their hands over a period of 15 years (1970-1985). 4 developed a Trichophyton rubrum infection, and the other 2 an irritant contact dermatitis. All of them carried out jobs which caused traumatization of the skin, due to the presence of eth...

journal_title：Contact dermatitis

authors： Skogstad M,Levy F

更新日期：1994-07-01 00:00:00

abstract：:From February 1989 to January 1990, the Swiss Contact Dermatitis Research Group conducted a 1-year study to examine the frequency of sensitization to a series of 13 common preservatives. A group of 2295 consecutive outpatients with suspected allergic contact dermatitis (age range 7-90 years, with a mean age of 42; 911...

journal_title：Contact dermatitis

authors： Perrenoud D,Bircher A,Hunziker T,Suter H,Bruckner-Tuderman L,Stäger J,Thürlimann W,Schmid P,Suard A,Hunziker N

更新日期：1994-05-01 00:00:00

abstract：:Murine models for the assessment of the contact sensitizing properties of chemicals rely on mouse ear swelling tests (Mest), which are not sensitive enough to detect weak sensitizers. The aim of the present study was to develop in mice an adjuvant-free Mest appropriate for in vivo detection of any type of sensitizer (...

journal_title：Contact dermatitis

authors： Garrigue JL,Nicolas JF,Fraginals R,Benezra C,Bour H,Schmitt D

更新日期：1994-04-01 00:00:00

abstract：:To estimate the prevalence of hand eczema, a questionnaire was distributed to 901 male car mechanics. Of the 801 persons who responded, 15% reported hand eczema on some occasion in the previous 12 months, and 57% admitted dry skin on the hands. In a 2nd part of the study, those who reported hand eczema were examined a...

journal_title：Contact dermatitis

authors： Meding B,Barregård L,Marcus K

更新日期：1994-03-01 00:00:00

abstract：:The irritation potential of surfactants and body cleansing products was determined by evaluating the removal of dansyl chloride from the skin. Dilute solutions (2% active ingredient, w/v) of surfactants and soap extract fluorescence from the skin within 30 min. This is probably a physicochemical effect as it is too ra...

journal_title：Contact dermatitis

authors： Paye M,Simion FA,Pierard GE

更新日期：1994-02-01 00:00:00

abstract：:Despite the frequency of irritant contact dermatitis, very little is known about the duration of barrier function impairment following cumulative irritant contact dermatitis. We studied post-irritation irritant reactivity by assessing the response to SLS irritation in previously irritated sites. Cumulative irritant co...

journal_title：Contact dermatitis

authors： Widmer J,Elsner P,Burg G

更新日期：1994-01-01 00:00:00

abstract：:Drug reactions are a common problem in hospital inpatients and outpatients. Oral or parenteral drug challenges are valuable diagnostic aids, but time consuming. We review attempts to diagnose delayed hypersensitivity drug eruptions by patch testing. We review control data, and offer an operational definition that migh...

journal_title：Contact dermatitis

authors： Calkin JM,Maibach HI

更新日期：1993-11-01 00:00:00

abstract：:In an evaluation of the safety of new chemicals, of products containing them, or of novel formulations of existing chemicals which may come into contact with the skin, it is important to incorporate an assessment of specially susceptible sub-populations. Such a group is represented by those who are more likely to expe...

journal_title：Contact dermatitis

authors： Basketter DA,Griffiths HA

更新日期：1993-10-01 00:00:00

abstract：:A popular "skin protector" consisting of an emulsion-like foam of lipophilic and hydrophilic substances (Marly skin) was evaluated in a previously described repetitive irritation guinea pig model. The product failed to inhibit the irritation due to sodium lauryl sulphate and toluene. In striking contrast to the recomm...

journal_title：Contact dermatitis

authors： Frosch PJ,Schulze-Dirks A,Hoffmann M,Axthelm I

更新日期：1993-08-01 00:00:00

abstract：:Several acetogenins, characteristic of the Annonaceae, have been found to exhibit pesticidal and feeding-deterrent activities against a variety of pests and are undergoing commercial development as pesticides. The sensitizing potential of one of these plants, pawpaw, Asimina triloba Dunal, was examined in the current ...

journal_title：Contact dermatitis

authors： Avalos J,Rupprecht JK,McLaughlin JL,Rodriguez E

更新日期：1993-07-01 00:00:00